Innovative Bioanalytical Tools Combining Microfluidics and Plasmonics for Cell Screening Purposes

Microfluidics for cell-based high throughput screening platforms - A review.

In the last decades, the basic techniques of microfluidics for the study of cells such as cell culture, cell separation, and cell lysis, have been well developed. Based on cell handling techniques, microfluidics has been widely applied in the field of PCR (Polymerase Chain Reaction), immunoassays, organ-on-chip, stem cell research, and analysis and identification of circulating tumor cells. As ...

English for Specific Purposes: Proposing an Innovative Approach to Teaching English to Medical Students

Background: English for Specific Purposes (ESP) courses should empower students to satisfy their language needs. However, at many Iranian universities, these courses are mostly taught based on the Grammar Translation Method focusing on teaching grammatical rules and reading comprehension. The present study aims at proposing an innovative approach for teaching English to Medical students that ca...

Quality assessment : many tools for many purposes

Functional single-cell hybridoma screening using droplet-based microfluidics.

Monoclonal antibodies can specifically bind or even inhibit drug targets and have hence become the fastest growing class of human therapeutics. Although they can be screened for binding affinities at very high throughput using systems such as phage display, screening for functional properties (e.g., the inhibition of a drug target) is much more challenging. Typically these screens require the g...

Acousto-microfluidics for screening of ssDNA aptamer

We demonstrate a new screening method for obtaining a prostate-specific antigen (PSA) binding aptamer based on an acoustofluidic separation (acoustophoreis) technique. Since acoustophoresis provides simultaneous washing and separation in a continuous flow mode, we efficiently obtained a PSA binding aptamer that shows high affinity without any additional washing step, which is necessary in other...